Dr. Omar Jina, CCO, Syrris
The use of flow chemistry methods in the synthesis of chemical compounds is well documented to give a wide range of benefits over traditional batch methods. The use of reactive gases under these conditions is not so readily explored however. The use of reactive gases in research laboratories is often under used due to issues with safety concerns, the containment of pressurized gases and associated costs of scaling up these reactions.
The use of flow chemistry methods can overcome these problems, often giving cleaner reactions, increased cost efficiency and ease of work-up.
I wanted to demonstrate an easy-to-use, safe, continuous method for the introduction of reactive gases in a liquid/gas plug-flow method under anhydrous conditions.
Watch my video below to see the synthesis of a carboxylic acid from a Grignard reagent using CO2 gas directly introduced into a micro-reactor. Enjoy!
About Dr. Omar Jina
Omar’s role as Chief Commercial Officer includes overseeing Marketing, Sales, Product Management, Application & Support of all Blacktrace brands (Syrris is one of 5 Blacktrace brands). Read Omar’s bio here.
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So why should your lab consider performing your chemistry using continuous flow chemistry techniques? Discover several reasons including faster and reactions, and accessing novel chemistries not possible in batch
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